Synlett

An efficient new procedure for the one-pot conversion of aldehydes into the corresponding nitriles

JL Zhu, FY Lee, JD Wu, CW Kuo, KS Shia

Index: Zhu, Jia-Liang; Lee, Fa-Yen; Wu, Jen-Dar; Kuo, Chun-Wei; Shia, Kak-Shan Synlett, 2007 , # 8 p. 1317 - 1319

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Citation Number: 20

Abstract

Abstract A new and efficient procedure for the one-pot conversion of various aldehydes into the corresponding nitriles under mild reaction conditions has been developed. The ethyl dichlorophosphate/DBU-mediated dehydration of aldoxime intermediates was utilized as a key operation to effect the transformation.

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