Green Chemistry

Synthesis of phenacyl bromides via K 2 S 2 O 8-mediated tandem hydroxybromination and oxidation of styrenes in water

Q Jiang, W Sheng, C Guo

Index: Jiang, Qing; Sheng, Wenbing; Guo, Cancheng Green Chemistry, 2013 , vol. 15, # 8 p. 2175 - 2179

Full Text: HTML

Citation Number: 16

Abstract

Non-transition metal-catalyzed synthesis of phenacyl bromides was achieved through K2S2O8-mediated tandem hydroxybromination and oxidation of styrenes. The advantages of this reaction are its excellent functional group compatibility, mild reaction conditions (60° C) and use of pure water as reaction medium. Based upon experimental observations, a plausible reaction mechanism is proposed.