Tetrahedron letters

2-Phenyl isopropyl and t-butyl trichloroacetimidates: Useful reagents for ester preparation of N-protected amino acids under neutral conditions

J Thierry, C Yue, P Potier

Index: Thierry, Josiane; Yue, Chongwei; Potier, Pierre Tetrahedron Letters, 1998 , vol. 39, # 12 p. 1557 - 1560

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Citation Number: 41

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... 2-Phenylisopropyl and t-butyl trichloroacetamidates 1 and 2 are useful reagents for the esterification of N-protected aminoacids under mild neutral conditions. In the case of hydroxyl-containing amino acids, dialkylation occurs but no selectivity could be obtained. ... A mixture of CH 2 Cl 2 ...