Benzenesulfonylcarbonitrile oxide. 4. Substitution reactions of 3-phenylsulfonylisoxazolines

…, SA Hardinger, MK Pillay, NV Amin…

Index: Wade, P. A.; Yen, H.-K.; Hardinger, S. A.; Pillay, M. K.; Amin, N. V.; et al. Journal of Organic Chemistry, 1983 , vol. 48, # 11 p. 1796 - 1800

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Citation Number: 19

Abstract

8 9 nyllithium, reactions can be conducted at-70 OC and are complete in 10 min, affording the products listed in Table I. Lithium phenylacetylide is slower to react and requires 0" C but otherwise is similar in ita behavior. One Grignard reagent, methylmagnesium bromide, has also been investigated and does react, although at a distinctly slower rate than any of the lithium reagents. Weaker carbon nucleophiles may be employed under more vigorous ...