A Versatile Synthesis, PM3??Semiempirical, Antibacterial, and Antitumor Evaluation of Some Bioactive Pyrazoles

…, HG El??Gohary, M Soliman, HH Zoorob

Index: Hamama, Wafaa S.; El-Gohary, Hamada G.; Soliman, Mamdouh; Zoorob, Hanfi H. Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 3 p. 543 - 554

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Citation Number: 6

Abstract

Abstract This research work describes the synthesis and biological properties of some novel isolated or fused heterocyclic ring systems with pyrazole, for example; enaminones containing pyrazolone ring photochromic functional unit, 4-[(4-chlorophenylamino) methylene]-3-methyl-1-phenyl-1H-pyrazol-5 (4H)-one (3) and some analogous derivatives 4, 9, and 10, also as pyrazolo [3, 4-b] pyridine, pyrazolo [3, 4-b] quinoline, pyrazolo [3′, 4 ...