Chemical Communications

Copper (ii)-catalyzed highly diastereoselective three-component reactions of aryl diazoacetates with alcohols and chalcones: an easy access to furan derivatives

Y Zhu, C Zhai, L Yang, W Hu

Index: Zhu, Yingguang; Zhai, Changwei; Yang, Liping; Hu, Wenhao Chemical Communications, 2010 , vol. 46, # 16 p. 2865 - 2867

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Citation Number: 22

Abstract

Copper (II) complexes are efficient catalysts in three-component reactions of aryl diazoacetates with alcohols and chalcones to give γ-hydroxyketone derivatives in high yield with excellent diastereoselectivity. The resulting coupling adducts can be easily converted into furan-containing oligoaryls, tetrahydrofuran and 2, 3-dihydrofuran derivatives.