Improved synthesis of aryltrialkoxysilanes via treatment of aryl Grignard or lithium reagents with tetraalkyl orthosilicates

…, R Correia, WM Seganish, P DeShong

Index: Seganish, W. Michael; DeShong, Philip Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6790 - 6795

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Citation Number: 68

Abstract

General reaction conditions for the synthesis of aryl (trialkoxy) silanes from aryl Grignard and lithium reagents and tetraalkyl orthosilicates (Si (OR) 4) have been developed. Ortho-, meta- , and para-substituted bromoarenes underwent efficient metalation and silylation at low temperature to provide aryl siloxanes. Mixed results were obtained with heteroaromatic substrates: 3-bromothiophene, 3-bromo-4-methoxypyridine, 5-bromoindole, and N-methyl ...