Fitoterapia

Design, synthesis and biological evaluation of paclitaxel-mimics possessing only the oxetane D-ring and side chain structures

XX Chen, F Gao, Q Wang, X Huang, D Wang

Index: Fitoterapia, , vol. 92, p. 111 - 115

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Citation Number: 9

Abstract

... Fitoterapia. Volume 92, January 2014, Pages 111–115. ... To a solution of KOH (179 g, 3.2 mol) and p-tosylamide (205 g, 1.2 mol) in 1500 mL ethanol, 3-bromo-2,2-bis(bromomethyl)propan- 1-ol (324 g, 1.0 mol) was added at room temperature and the reaction mixture was heated ...