Synthesis of (Arylalkenyl) silanes by Palladium-Catalyzed Regiospecific and Stereoselective Allyl Transfer from Silyl-Substituted Homoallyl Alcohols to Aryl Halides

S Hayashi, K Hirano, H Yorimitsu…

Index: Iwasaki, Masayuki; Hayashi, Sayuri; Hirano, Koji; Yorimitsu, Hideki; Oshima, Koichiro Journal of the American Chemical Society, 2007 , vol. 129, # 14 p. 4463 - 4469

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Citation Number: 45

Abstract

The reactions of silyl-substituted homoallyl alcohols with aryl halides under palladium catalysis result in regiospecific and stereoselective allyl transfer from the alcohols to aryl halides, offering modular synthesis of (E)-3-aryl-1-alkenyl-,(E)-1-aryl-2-alkenyl-, and optically active (E)-1-aryl-2-butenylsilanes.