Synthesis and antifungal activities of natural and synthetic biflavonoids

G Sagrera, A Bertucci, A Vazquez, G Seoane

Index: Sagrera, Gabriel; Bertucci, Ana; Vazquez, Alvaro; Seoane, Gustavo Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 10 p. 3060 - 3073

Full Text: HTML

Citation Number: 22

Abstract

Abstract The synthesis of some natural and synthetic biflavonoids was performed in good overall yields starting from readily available materials via high yielding aldol and Ullmann condensations. Some of these compounds, especially bichalcones, display an interesting activity against fungi, higher than that of the corresponding monomers.

~72%

~10%

~79%

~76%

~92%

~88%

Ionic liquid catalyzed expeditious synthesis of 2??aryl??2, ...

[Eshghi, Hossein; Rahimizadeh, Mohammad; Mousavi, Seyed Mohsen Natural Product Research, 2014 , vol. 28, # 7 p. 438 - 443]

Synthesis of flavanones by use of anhydrous potassium carbon...

[Mondal, Rina; Gupta, Arpita Das; Mallik, Asok K. Tetrahedron Letters, 2011 , vol. 52, # 39 p. 5020 - 5024]

Synthesis of flavanones, azaflavanones, and thioflavanones c...

[Sakirolla, Raghavendra; Yaeghoobi, Marzieh; Rahman, Noorsaadah Abd. Monatshefte fur Chemie, 2012 , vol. 143, # 5 p. 797 - 800]

Synthesis of chalcones and flavanones using Julia–Kocienski ...

[Kumar, Atul; Sharma, Siddharth; Tripathi, Vishwa Deepak; Srivastava, Suman Tetrahedron, 2010 , vol. 66, # 48 p. 9445 - 9449]