An initial study of the side-chain unsubstituted 2'-hydroxyacrylophenone system shows it to have a considerably greater propensity for intermolecular addition than the comparable 2'- hydroxychalcone system, readily undergoing base-catalysed addition of, for example, alcohol and thereby diverting typical chalcone reactions requiring alcoholic alkali. 2'- Acetoxyacrylophenone dibromides and bromoalkoxides cyclize with base to chromone ...
