Regioselective synthesis of 2-and 3-substituted imidazo [1, 2-a] pyridines

…, X Cong, J He, S Luo, D Wu, J Lan

Index: Liu, Guoping; Cong, Xuefeng; He, Jiaheng; Luo, Shunzhong; Wu, Di; Lan, Jingbo Journal of Chemical Research, 2012 , vol. 36, # 12 p. 687 - 690

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Abstract

Imidazo[1,2-a]pyridines are a class of compounds that possess a wide range of pharmacological properties including anti- bacterial, antifungal, antiviral, anti-inflammatory activities.1,2 They can also be used for prophylactic and therapeutic treat- ment of anxiety, diabetes, hyperglycaemia, hypertension, and arteriosclerosis.3 Several drugs based on imidazo[1,2-a] pyridine are already on the market including alpidem, necopi- dem, saripidem, zolimidine ...