The Journal of organic chemistry

Bromodecarboxylation of quinoline salicylic acids: increasing the diversity of accessible substituted quinolines

K Janz, N Kaila

Index: Janz, Kristin; Kaila, Neelu Journal of Organic Chemistry, 2009 , vol. 74, # 22 p. 8874 - 8877

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Citation Number: 11

Abstract

Quinoline salicylic acids underwent bromodecarboxylation at room temperature upon treatment with N-bromosuccinimide. A wide variety of functional groups was tolerated. Several one-pot transformations were also carried out, allowing the preparation of diverse 4- substituted quinolines.