A reductive amination of carbonyls with amines using decaborane in methanol

JW Bae, SH Lee, YJ Cho, CM Yoon

Index: Bae, Jong Woo; Lee, Seung Hwan; Cho, Young Jin; Yoon, Cheol Min Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 2 p. 145 - 146

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Citation Number: 35

Abstract

Reductive amination is an important synthetic method in organic synthesis, in which carbonyl compounds and amines are mixed with reducing agents. A variety of reducing agents are known to effect reductive amination of aldehydes and ketones. These are hydrogen in the presence of metal catalyst, 1 sodium borohydride, 2 borane–pyridine, 3 borohydride exchange resin (BER), 4 zinc–acetic acid, 5 sodium borohydride–magnesium perchlorate, 6 zinc ...