α-Fluoro-2, 2, 3, 3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid

N Pessah, M Bialer, B Wlodarczyk…

Index: Zhang, Lian Hao; Duan, Jianxin; Xu, Yuelian; Dolbier Jr., William R. Tetrahedron Letters, 1998 , vol. 39, # 52 p. 9621 - 9622

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Citation Number: 31

Abstract

... Volume: Page ... OH, 0 °C. In preparation of amide 12 (R = NHCH 3 ): methylamine, 0 °C. In preparation of amide 13 (R = NHCONH 2 ... such as the Hell−Volhard−Zelinski reaction frequently used for α-halogenations of carboxylic acids.(38, 39) Therefore, syntheses ...