Efficient synthesis of olmesartan medoxomil, an antihypertensive drug

…, S Sebastian, MS Varma, G Venkateswarlu…

Index: Babu, Karrothu Srihari; Reddy, Mallepalli Srinivasa; Tagore, Amirisetty Ravindranath; Reddy, Gade Srinivas; Sebastian, Sony; Varma, Mudunuru Satish; Venkateswarlu, Gandu; Bhattacharya, Apurba; Reddy, Padi Pratap; Anand, Ramasamy Vijaya Synthetic Communications, 2009 , vol. 39, # 2 p. 291 - 298

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Citation Number: 6

Abstract

Abstract This document describes a simple and robust process for the synthesis of olmesartan medoxomil. This tailored process allows us to synthesize olmesartan medoxomil on a large scale with 50% overall yield. Also, our process has excellent control of the impurity profile in all the stages.