Organic letters

Palladium-Catalyzed Silylation of Aryl Bromides Leading to Functionalized Aryldimethylsilanols

SE Denmark, JM Kallemeyn

Index: Denmark, Scott E.; Kallemeyn, Jeffrey M. Organic Letters, 2003 , vol. 5, # 19 p. 3483 - 3486

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Citation Number: 57

Abstract

A mild and general palladium-catalyzed insertion of 1, 2-diethoxy-1, 1, 2, 2- tetramethyldisilane into a variety of aryl bromides affords the aryldimethylsilyl ethers in high yields. Hydrolysis of the ethers under pH-optimized conditions results in the exclusive formation of the desired aryldimethylsilanols.