Biological and Pharmaceutical Bulletin

Blue fluorescence generated during lipid oxidation of rat liver microsomes cannot be derived from malonaldehyde but can be from other aldehyde species.

T Inoue, K Kikugawa

Index: Inoue, Tadamichi; Kikugawa, Kiyomi Biological and Pharmaceutical Bulletin, 1998 , vol. 21, # 4 p. 319 - 325

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Citation Number: 11

Abstract

Generation of blue fluorescence together with phospholipid hydroperoxides and aldehyde species in rat liver microsomes during oxidation with FeCl 2-ADP-ascorbic acid was monitored, and the kind of lipid oxidation products participating in the formation of blue fluorescence was investigated. Contents of phospholipid hydroperoxides were incresed in an early stage of oxidation, and were decreased in an advanced stage of oxidation. ...

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