Singlet oxygen oxidation of substituted furans to 5-hydroxy-2 (5H)-furanone

…, ET Syage, DA Harcourt, JM Holmes…

Index: Lee, Gary C. M.; Syage, Elizabeth T.; Harcourt, Dale A.; Holmes, Judy M.; Garst, Michael E. Journal of Organic Chemistry, 1991 , vol. 56, # 25 p. 7007 - 7014

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Citation Number: 48

Abstract

The conditions for the regiospecific-let oxygen oxidation of various 2, 4&ubstituted furans 9 to 4substituted-2 (5H)-furanones 3 are developed. The presence of a C-2 substituent (eg, trimethylsdyl, tert-butyldimethylsilyl, or tributylstannyl) in 9 is an absolute requirement for ...