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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Asymmetric chemoenzymatic synthesis of ramatroban using lipases and oxidoreductases

E Busto, V Gotor-Fernández…

Index: Journal of Organic Chemistry, , vol. 77, # 10 p. 4842 - 4848

Full Text: HTML

Citation Number: 29

Abstract

... The Journal of Organic ... J. Org. Chem. ... fashion.(2) Biotransformations offer some clear advantages in comparison with traditional chemical processes, as they generally occur under environmentally friendly reaction conditions,(3) avoiding the use of hazardous organic reagents or ...

 Related Synthetic Route
1,4-Dioxaspiro[4.5]decan-8-one Structure

4746-97-8

1,4-Dioxaspiro[...

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
(+/-)-2,3,4,9-tetrahydro-1H-carbazol-3-ol Structure

128432-38-2

(+/-)-2,3,4,9-t...

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
Phenylhydrazine Structure

100-63-0

Phenylhydrazine

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
5-oxo-tetrahydrocarbazole ethylene ketal Structure

54621-12-4

5-oxo-tetrahydr...

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
(S)-(-)-2,3,4,9-tetrahydro-1H-carbazol-3-ol Structure

1374648-14-2

(S)-(-)-2,3,4,9...

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
(S)-2,3,4,9-tetrahydro-1H-carbazol-3-yl methanesulfonate Structure

1374648-17-5

(S)-2,3,4,9-tet...

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
4-fluoro-N-(2,3,4,9-tetrahydro-1H-carbazol-3-yl)benzenesulfonamide Structure

116650-12-5

4-fluoro-N-(2,3...

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
2,3,4,9-Tetrahydro-1H-carbazol-3-amine Structure

61894-99-3

2,3,4,9-Tetrahy...

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
N/A Structure

1374648-18-6

N/A

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
chloro(4-fluorophenyl)sulfone Structure

349-88-2

chloro(4-fluoro...

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
N/A Structure

116650-36-3

N/A

~%

Ramatroban Structure

116649-85-5

Ramatroban

Learn More
Phenylhydrazine Structure

100-63-0

Phenylhydrazine

~%

2,3,4,9-Tetrahydro-1H-carbazol-3-amine Structure

61894-99-3

2,3,4,9-Tetrahy...

Learn More
5-oxo-tetrahydrocarbazole ethylene ketal Structure

54621-12-4

5-oxo-tetrahydr...

~%

2,3,4,9-Tetrahydro-1H-carbazol-3-amine Structure

61894-99-3

2,3,4,9-Tetrahy...

Learn More
1,4-Dioxaspiro[4.5]decan-8-one Structure

4746-97-8

1,4-Dioxaspiro[...

~%

2,3,4,9-Tetrahydro-1H-carbazol-3-amine Structure

61894-99-3

2,3,4,9-Tetrahy...

Learn More
Related Articles: More...
Chemoenzymatic Asymmetric Synthesis of Serotonin Receptor Ag...

[Busto, Eduardo; Gotor-Fernandez, Vicente; Gotor, Vicente Journal of Organic Chemistry, 2012 , vol. 77, # 10 p. 4842 - 4848]
Synthesis and absolute configuration of the new thromboxane ...

[Arzneimittel-Forschung/Drug Research, , vol. 39, # 12 p. 1519 - 1521]
Synthesis and absolute configuration of the new thromboxane ...

[Arzneimittel-Forschung/Drug Research, , vol. 39, # 12 p. 1519 - 1521]
Synthesis and absolute configuration of the new thromboxane ...

[Arzneimittel-Forschung/Drug Research, , vol. 39, # 12 p. 1519 - 1521]

Detail Synthetic Route


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