e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Design, Synthesis, Computational Prediction, and Biological Evaluation of Ester Soft Drugs as Inhibitors of Dihydrofolate Reductase from Pneumocystis c arinii

M Graffner-Nordberg, K Kolmodin, J Åqvist…

Index: Taylor, Edward C.; Otiv, S. R.; Durucasu, Inci Heterocycles, 1993 , vol. 36, # 8 p. 1883 - 1895

Full Text: HTML

Citation Number: 88

Abstract

... Volume: Page: ... 32,36,38 Today, considerable research efforts are devoted to the identification of more selective and potent DHFR inhibitors with the ... a Reagents and conditions: (i) (a) H 2 , 10% Pd/C, Et 3 N, DMF, (b) guanidine hydrochloride, NaOMe, reflux; (ii ...

6-bromo-4-ethoxy-2-pivaloylamino-5-deazapteridine Structure

6-bromo-4-ethox...

~85%

2-Amino-6-bromopyrido[2,3-d]pyrimidin-4(3H)-one Structure

2-Amino-6-bromo...

N/A Structure

~91%

2,4-Pteridinediamine,6-methyl- Structure

2,4-Pteridinedi...

6-METHYLPTERINE Structure

6-METHYLPTERINE

~%

2,4-Pteridinediamine,6-methyl- Structure

2,4-Pteridinedi...

6-methyl-2-pivaloylamino-4(3H)-pteridinone Structure

6-methyl-2-piva...

~%

2,4-Pteridinediamine,6-methyl- Structure

2,4-Pteridinedi...

6-methyl-2-pivaloylamino-4-[1'-(1,2,4-triazolyl)]pteridine Structure

6-methyl-2-piva...

~%

2,4-Pteridinediamine,6-methyl- Structure

2,4-Pteridinedi...

N/A Structure

~81%

6-bromopyrido[2,3-d]pyrimidine-2,4-diamine Structure

6-bromopyrido[2...

N-(6-bromo-4-hydroxypyrido[2,3-d]pyrimidin-2-yl)pivalamide Structure

N-(6-bromo-4-hy...

~%

6-bromopyrido[2,3-d]pyrimidine-2,4-diamine Structure

6-bromopyrido[2...

N/A Structure

~%

6-bromopyrido[2,3-d]pyrimidine-2,4-diamine Structure

6-bromopyrido[2...

N/A Structure

~65%

2,4-Pteridinediamine,6,7-diphenyl- Structure

2,4-Pteridinedi...

6,7-diphenyl-2-pivaloylamino-4(3H)-pteridinone Structure

6,7-diphenyl-2-...

~%

2,4-Pteridinediamine,6,7-diphenyl- Structure

2,4-Pteridinedi...

N/A Structure

~%

2,4-Pteridinediamine,6,7-diphenyl- Structure

2,4-Pteridinedi...

奈米碳管軟性透光導電薄膜之製備

[Taylor, Edward C.; Yoon, Cheol-min Synthetic Communications, 1988 , vol. 18, # 11 p. 1187 - 1192]

Protection and deprotection of fused 2-amino-4 (3H)-pyrimidi...

[Heterocycles, , vol. 36, # 8 p. 1883 - 1895]

Protection and deprotection of fused 2-amino-4 (3H)-pyrimidi...

[Heterocycles, , vol. 36, # 8 p. 1883 - 1895]