Tetrahedron letters

A chemical model for the activation of pyruvate-formate-lyase

JE Baldwin, D Brown, PH Scudder, ME Wood

Index: Baldwin, Jack E.; Brown, David; Scudder, Paul H.; Wood, Mark E. Tetrahedron Letters, 1995 , vol. 36, # 12 p. 2105 - 2108

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Citation Number: 8

Abstract

A chemical model is described for the activation of the carbon-centred radical-based enzyme, pyruvate-formate-lyase. The feasibility of a 5′-deoxyadenosyl radical abstracting a hydrogen atom from C-2 of a peptideglycine residue has been demonstrated in an intramolecular process.

6066-82-6

N-Hydroxysuccinimide

~84%

Synthesis and neuroprotective activity of analogues of glycy...

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