Synthesis of trans-2-[N-(2-Hydroxy-1, 2, 3, 4-tetrahydronaphthalene-1-yl)] iminothiazolidine and Related Compounds-A New Class of Antidepressants

…, R Singh, JM Khanna, AK Saxena…

Index: Shukla, Upendra K.; Singh, Raieshwar; Khanna, J. M.; Saxena, Anil K.; Singh, Hemant K.; et al. Collection of Czechoslovak Chemical Communications, 1992 , vol. 57, # 2 p. 415 - 424

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Citation Number: 16

Abstract

Abstract Antiparasitic and antidepressant activities exhibited by tetramisole (I) and its enantiomers prompted the study of its structural analogs trans-2-[N-(2-hydroxy-1, 2, 3, 4- tetrahydronaphthalene/indane-1-yl)] iminothiazolidine (VIII/IX) and 2, 3, 4a, 5, 6, 10b- hexahydronaphtho [1', 2': 4, 5]-imidazo [2, 1-b] thiazole (XII), 2, 3, 4a, 5-tetrahydro-9bH- indeno [1', 2': 4, 5] imidazo [2, 1-b] thiazole (XIII), and 2, 3, 4a, 5-tetrahydro-9bH-indeno [1', ...