3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists

SP Walsh, A Severino, C Zhou, J He, GB Liang…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 11 p. 3390 - 3394

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Citation Number: 19

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... 8 This letter describes the synthesis and biological activity of a series of β-substituted propionic acids with improved potency. ...

3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 ago...

[Walsh, Shawn P.; Severino, Alexandra; Zhou, Changyou; He, Jiafang; Liang, Gui-Bai; Tan, Carina P.; Cao, Jin; Eiermann, George J.; Xu, Ling; Salituro, Gino; Howard, Andrew D.; Mills, Sander G.; Yang, Lihu Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3390 - 3394]