Selective cleavage of O-(dimethoxytrityl) protecting group with sodium periodate

…, Z Točík, R Liboska, I Rosenberg

Index: Rejman, Dominik; Kralikova, Sarka; Tocik, Zdenek; Liboska, Radek; Rosenberg, Ivan Collection of Czechoslovak Chemical Communications, 2002 , vol. 67, # 4 p. 502 - 508

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Citation Number: 4

Abstract

Abstract Sodium periodate in aqueous organic solvents selectively removes, under mild reaction conditions, the O-(dimethoxytrityl) protecting group. Selectivity of the cleavage was studied using the nucleoside derivatives protected by various types of groups commonly used in nucleoside and nucleotide chemistry.