A general method is described for the formation of furanoid and pyranoid glycals. Thus, lithium-ammonia reduction of the corresponding l-chloro-2, 3-0-isopropylidene furanoid and pyranoid carbohydrate derivatives affords the desired glycals in 87-92% yields. Several examples that reveal the scope of this process are described. The formation of C-glycosides from the glycal esters through application of the ester enolate Claisen rearrangement is ...
