Arkivoc

Triazolopyridines. Part 30. Hydrogen transfer reactions; pyridylcarbene formation

…, R Adam, S Alom, R Ballesteros, S López-Molina

Index: Abarca, Belen; Adam, Rosa; Alom, Shamim; Ballesteros, Rafael; Lopez-Molina, Sonia Arkivoc, 2014 , vol. 2014, # 2 p. 175 - 186

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Abstract

Abstract The transfer hydrogenation reaction of [1, 2, 3] triazolo [1, 5-a] pyridines with Pd/C/Zn or Pd (OH) 2/C/Zn in water, ethanol or water/ethanol mixture has been explored. 4, 5, 6, 7-Tetrahydrotriazolopyridines were obtained in good to medium yields. In addition, under the same conditions 2-substituted pyridines were also formed as a result of intermediate pyridylcarbene formation, by triazole ring opening and loss of nitrogen. ...