piconol

Modify Date: 2026-07-07 14:27:32

piconol Structure
piconol structure
Common Name piconol
CAS Number 586-98-1 Molecular Weight 109.126
Density 1.1±0.1 g/cm3 Boiling Point 222.6±0.0 °C at 760 mmHg
Molecular Formula C6H7NO Melting Point 5 °C
MSDS Chinese USA Flash Point 81.7±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of piconol


2-Pyridinemethanol is a pyridylalcohol, with hypoglycemic activity[1].

 Names

Name 2-(Hydroxymethyl)pyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 222.6±0.0 °C at 760 mmHg
Melting Point 5 °C
Molecular Formula C6H7NO
Molecular Weight 109.126
Flash Point 81.7±20.4 °C
Exact Mass 109.052765
PSA 33.12000
LogP -0.46
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.551
InChIKey SHNUBALDGXWUJI-UHFFFAOYSA-N
SMILES OCc1ccccn1
Storage condition 2-8°C
Water Solubility miscible

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT4689000
CHEMICAL NAME :
2-Pyridinemethanol
CAS REGISTRY NUMBER :
586-98-1
BEILSTEIN REFERENCE NO. :
0107849
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H7-N-O
MOLECULAR WEIGHT :
109.14
WISWESSER LINE NOTATION :
T6NJ B1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 11,242,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UT4689000
HS Code 29333999

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
Self-assembled hybrid metal oxide base catalysts prepared by simply mixing with organic modifiers.

Nat. Commun. 6 , 8580, (2015)

Multidentate materials formed by simply mixing heterogeneous and homogeneous components are promising for construction of versatile active sites on the surface of heterogeneous compounds, however, to ...

 piconolBioassay

View more

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: Hypoglycemic activity in 48 hrs fasted Charles River rat at 150 mg/kg, po measured at...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL3231521
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898
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 Synonyms

2-PYRIDYLCARBINOL
Pyridine-2-carbinol
2-Pyridinylmethanol
(pyridin-2-yl)methanol
a-Picolyl Alcohol
2-HMP
piconol
EINECS 209-592-7
2-PICOLYL ALCOHOL
2-hydroxymethylpyridine
picolinyl alcohol
2-Pyridinemethanol
pyridin-2-ylmethanol
2-PYRIDYLMETHANOL
2-Pyridine
α-Picolyl alcohol
MFCD00006348
pyridine-2-ylmethanol
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