An efficient synthesis of [D6] leucocrystal violet

W Yang, Y Luo, W Liu, X Deng, X Du…

Index: Yang, Weicheng; Luo, Yong; Liu, Weixia; Deng, Xiaojun; Du, Xiaoning; Li, Meihua Journal of Labelled Compounds and Radiopharmaceuticals, 2011 , vol. 54, # 4 p. 211 - 213

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Abstract

Abstract This report presents an efficient synthesis of [D 6] leucocrystal violet. Esterification of p-toluenesulphonyl chloride with [D 4] methanol provided [D 3] methyl p- toluenesulphonate, which was used to methylate aniline to give [D 6] N, N-dimethylaniline. Condensation of [D 6] N, N-dimethylaniline with bis [4-(dimethylamino) phenyl] methanol afforded [D 6] leucocrystal violet in an overall yield of 30% in three steps. Copyright© 2010 ...