Unsymmetrically Substituted Piperazines. IX. Quaternary Salts of Benzhydrylpiperazines as Spasmolytics1

R Baltzly, WS Ide, E Lorz

Index: Ide et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 3142

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Citation Number: 8

Abstract

A considerable number of N-benzhydryl-N'-alkylpiperazines have been prepared in the search for antihistaminic corn pound^.^^^ In that series, antihistaminic activity was favored notably by Fara substitution in one of the rings of the benzhydryl portion and was largely abolished by ortho or meta substitution.