methylpiperazine

Modify Date: 2024-01-02 22:37:22

methylpiperazine Structure
methylpiperazine structure
 Common Name methylpiperazine
CAS Number 109-01-3 Molecular Weight 100.162
Density 0.9±0.1 g/cm3 Boiling Point 138.0±8.0 °C at 760 mmHg
Molecular Formula C5H12N2 Melting Point -6 °C
MSDS Chinese USA Flash Point 42.2±0.0 °C
Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06		 Signal Word Danger

 Names

Name 1-Methylpiperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 138.0±8.0 °C at 760 mmHg
Melting Point -6 °C
Molecular Formula C5H12N2
Molecular Weight 100.162
Flash Point 42.2±0.0 °C
Exact Mass 100.100044
PSA 15.27000
LogP -0.18
Vapour density 3.5 (vs air)
Vapour Pressure 6.9±0.3 mmHg at 25°C
Index of Refraction 1.442
Storage condition Store under Nitrogen
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM1225000
CHEMICAL NAME :
Piperazine, 1-methyl-
CAS REGISTRY NUMBER :
109-01-3
BEILSTEIN REFERENCE NO. :
0102724
LAST UPDATED :
199701
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C5-H12-N2
MOLECULAR WEIGHT :
100.19
WISWESSER LINE NOTATION :
T6M DNTJ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,863,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,863,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2830 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1450 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
REFERENCE :
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 15,116,1979
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2740 mg/m3/2H
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 11,123,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1490 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15040 mg/kg/32D-I
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 11,123,1969

 Safety Information

Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger
Hazard Statements H226-H312-H314-H331
Precautionary Statements P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive
Risk Phrases R10;R21;R34
Safety Phrases S16-S26-S36/37/39-S45
RIDADR UN 2734 8/PG 2
WGK Germany 2
RTECS TM1225000
Packaging Group III
Hazard Class 3
HS Code 2933599090

 Synthetic Route

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

Piperazine, 1-methyl-
methyl piperazine
4-Methylpiperazine
Cyclizine Related Compound A
N-METHYL-PIPERAZINE
EINECS 203-639-5
N-Methylpiperazine
PIPERAZINE,1-METHYL
N'-Methylpiperazine
1-Methyl-piperazine
1-Methylpiperazine
MFCD00005966
methylpiperazine
N-METHYL PIPERAZINE
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Chemsrc provides methylpiperazine(CAS#:109-01-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of methylpiperazine are included as well.>> amp version: methylpiperazine

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