methylpiperazine

Modify Date: 2025-08-22 07:43:40

methylpiperazine structure	Common Name	methylpiperazine
	CAS Number	109-01-3	Molecular Weight	100.162
	Density	0.9±0.1 g/cm3	Boiling Point	138.0±8.0 °C at 760 mmHg
	Molecular Formula	C₅H₁₂N₂	Melting Point	-6 °C
	MSDS	Chinese USA	Flash Point	42.2±0.0 °C
	Symbol	GHS02, GHS05, GHS06	Signal Word	Danger

Name	1-Methylpiperazine
Synonym	More Synonyms

Density	0.9±0.1 g/cm3
Boiling Point	138.0±8.0 °C at 760 mmHg
Melting Point	-6 °C
Molecular Formula	C₅H₁₂N₂
Molecular Weight	100.162
Flash Point	42.2±0.0 °C
Exact Mass	100.100044
PSA	15.27000
LogP	-0.18
Vapour density	3.5 (vs air)
Vapour Pressure	6.9±0.3 mmHg at 25°C
Index of Refraction	1.442
Storage condition	Store under Nitrogen
Water Solubility	soluble

methylpiperazine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM1225000

CHEMICAL NAME :: Piperazine, 1-methyl-

CAS REGISTRY NUMBER :: 109-01-3

BEILSTEIN REFERENCE NO. :: 0102724

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C5-H12-N2

MOLECULAR WEIGHT :: 100.19

WISWESSER LINE NOTATION :: T6M DNTJ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,863,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,863,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2830 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1450 mg/kg

TOXIC EFFECTS :: Behavioral - excitement Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 15,116,1979

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2740 mg/m3/2H

TOXIC EFFECTS :: Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 11,123,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1490 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15040 mg/kg/32D-I

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 11,123,1969

Symbol	GHS02, GHS05, GHS06
Signal Word	Danger
Hazard Statements	H226-H312-H314-H331
Precautionary Statements	P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C:Corrosive
Risk Phrases	R10;R21;R34
Safety Phrases	S16-S26-S36/37/39-S45
RIDADR	UN 2734 8/PG 2
WGK Germany	2
RTECS	TM1225000
Packaging Group	III
Hazard Class	3
HS Code	2933599090

Precursor 9
CAS#:111-42-2 dea CAS#:74-89-5 methylamine CAS#:325812-49-5 2-nitro-(N-meth... CAS#:110-85-0 Piperazine
CAS#:616-38-6 Dimethyl Carbonate CAS#:16339-07-4 Piperazine,1-me... CAS#:66739-87-5 1-Benzenesulfon... CAS#:105-59-9 N-Methyldiethan...
CAS#:62226-74-8 1-Benzyl-4-meth...
DownStream 10
CAS#:105396-59-6 3'-Hydroxy-5'-(... CAS#:100491-52-9 ethyl 6-fluoro-... CAS#:108372-23-2 1-Piperazinepro... CAS#:104712-26-7 [4-methoxy-2-[4...
CAS#:1053-74-3 2-Acetyl-10-[3-... CAS#:1059705-52-0 1-(3-chloro-4-n... CAS#:110358-10-6 1-Piperazinepro... CAS#:1093065-11-2 1-((3-Bromo-4-e...
CAS#:56323-03-6 4-(4-Methyl-1-p... CAS#:55480-45-0 3-(4-METHYLPIPE...

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Piperazine, 1-methyl-

methyl piperazine

4-Methylpiperazine

Cyclizine Related Compound A

N-METHYL-PIPERAZINE

EINECS 203-639-5

N-Methylpiperazine

PIPERAZINE,1-METHYL

N'-Methylpiperazine

1-Methyl-piperazine

1-Methylpiperazine

MFCD00005966

methylpiperazine

N-METHYL PIPERAZINE

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China
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China
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China
Product Name: methylpiperazine
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methylpiperazine

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