Indium-mediated regioselective synthesis of ketones from arylstannanes under solvent-free ultrasound irradiation

…, MA Badajoz, C Domini, AB Chopa, MT Lockhart

Index: Lo Fiego, Marcos J.; Badajoz, Mercedes A.; Domini, Claudia; Chopa, Alicia B.; Lockhart, Maria T. Ultrasonics Sonochemistry, 2013 , vol. 20, # 3 p. 826 - 832

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Citation Number: 8

Abstract

The solvent-free indium-promoted reaction of alkanoyl chlorides with sterically and electronically diverse arylstannanes is a simple and direct method for the regioselective synthesis of primary, secondary and tertiary alkyl aryl ketones in good to excellent isolated yields (42–84%) under mild and neutral conditions. The protocol is also adequate for the synthesis of aryl vinyl ketones. Reaction times are drastically reduced (from 3–32h to 10– ...