Abstract Methyl 3-amino-2-thiophene carboxylate reacts with orthoesters to produce N-(2- carbomethoxy thienyl) imidates 1. Treatment of these imidates with primary amines, hydrazine, methylhydrazine and phenylhydrazine yields only [3, 2-d] 4 (3H) thieno- pyrimidinones 2 and not isomeric 1, 3, 4-thienotriazepin-5-ones. The type of products obtained gave information relevant to the elucidation of the mechanism of cyclization and ...
![3-amino-2-methylthieno[3,2-d]pyrimidin-4-one Structure](https://image.chemsrc.com/caspic/328/143362-04-3.png)
