Methyl 3-amino-2-thiophenecarboxylate

Modify Date: 2024-01-02 14:32:41

Methyl 3-amino-2-thiophenecarboxylate Structure
Methyl 3-amino-2-thiophenecarboxylate structure
Common Name Methyl 3-amino-2-thiophenecarboxylate
CAS Number 22288-78-4 Molecular Weight 157.190
Density 1.3±0.1 g/cm3 Boiling Point 334.6±0.0 °C at 760 mmHg
Molecular Formula C6H7NO2S Melting Point 62-64 °C(lit.)
MSDS Chinese USA Flash Point 138.1±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name methyl 3-aminothiophene-2-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 334.6±0.0 °C at 760 mmHg
Melting Point 62-64 °C(lit.)
Molecular Formula C6H7NO2S
Molecular Weight 157.190
Flash Point 138.1±22.3 °C
Exact Mass 157.019745
PSA 80.56000
LogP 1.64
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.598

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S37/39-S36/37/39-S22
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS XM8347500
HS Code 2934999090

 Synthetic Route

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Methyl 3-amino-2-thiophenecarboxylate Structure

Methyl 3-amino-...

CAS#:22288-78-4

Literature: WO2010/101302 A1, ; Page/Page column 130 ; WO 2010/101302 A1

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Methyl 3-amino-2-thiophenecarboxylate Structure

Methyl 3-amino-...

CAS#:22288-78-4

Literature: US6503914 B1, ;

~75%

Methyl 3-amino-2-thiophenecarboxylate Structure

Methyl 3-amino-...

CAS#:22288-78-4

Literature: Synthetic Communications, , vol. 32, # 16 p. 2565 - 2568

~78%

Methyl 3-amino-2-thiophenecarboxylate Structure

Methyl 3-amino-...

CAS#:22288-78-4

Literature: US6503914 B1, ;

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Methyl 3-amino-2-thiophenecarboxylate Structure

Methyl 3-amino-...

CAS#:22288-78-4

Literature: European Journal of Medicinal Chemistry, , vol. 76, p. 343 - 351

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Methyl 3-amino-2-thiophenecarboxylate Structure

Methyl 3-amino-...

CAS#:22288-78-4

Literature: Synthetic Communications, , vol. 44, # 7 p. 1002 - 1006

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Tetrahedron Lett. 43(22) , 3993-96, (2002)

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Optimization of a series of constrained melanin-concentrating hormone receptor 1 (MCH R1) antagonists has provided compounds with potent and selective MCH R1 activity. Details of the optimization proc...

 Synonyms

methyl-3-amino-2-thiophene formate
3-Amino-2-thiophenecarboxylic Acid Methyl Ester
3-amino-2-thiophene carboxylic acid methyl ester
3-amino-2-carbomethoxythiophene
Methyl 3-aminothiophene-2-carboxylate
3-Amino-thiophene-2-carboxylic acid methyl ester
2-Thiophenecarboxylic acid, 3-amino-, methyl ester
Methyl 3-amino-2-thiophenecarboxylate
T5SJ BVO1 CZ
3-Aminothiophene-2-carboxylic acid methyl ester
EINECS 244-895-8
MFCD00009765
3-aminothiophen-2-carboxylic acid methyl ester
2-methoxycarbonyl-3-amino-thiophene
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