Journal of organometallic chemistry

Palladium-catalyzed coupling reactions of bromo-substituted phenylphosphine oxides: a facile route to functionalized arylphosphine ligands

L Xu, J Mo, C Baillie, J Xiao

Index: Xu, Lijin; Mo, Jun; Baillie, Colin; Xiao, Jianliang Journal of Organometallic Chemistry, 2003 , vol. 687, # 2 p. 301 - 312

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Citation Number: 25

Abstract

The Heck reaction of OPPh3− n (4-C6H4Br) n (n= 1–3) with electron deficient and neutral olefins led to linear olefin-substituted phenylphosphine oxides, whilst the reaction with an electron rich olefin in an ionic liquid solvent resulted in the formation of acetyl variants. The same bromophenylphosphine oxides also reacted with arylboronic acids under normal Suzuki coupling conditions, affording arylated phenylphosphine oxides in excellent yields. ...