A total synthesis of gascardic acid

RK Boeckman Jr, DM Blum…

Index: Boeckman,R.K. et al. Journal of the American Chemical Society, 1979 , vol. 101, p. 5060 - 5062

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Citation Number: 30

Abstract

In 1960, Brochere and Polonsky reported the isolation and characterization of a new C25 terpene acid called gascardic acid from Gascardia madagascariensis. I Preliminary data suggested that this substance represented a new structural class of the rare Czs sesterterpenes. Among the known sesterterpenes, the ophiobolane class (1) has over the years proven to