Tetrahedron letters

A facile and catalytic method for selective deprotection of tert-butyldimethylsilyl ethers with copper (II) bromide

S Bhatt, SK Nayak

Index: Bhatt, Suchitra; Nayak, Sandip K. Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8395 - 8399

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Citation Number: 14

Abstract

Copper (II) bromide is found to be a simple and efficient catalyst for selective deprotection of tert-butyldimethylsilyl ethers of alcohols/phenols at ambient temperature. Various labile functional groups such as ketal, alkene, ketone, OTBDPS, OTHP and allyl and benzyl ethers are found to be compatible under the reaction conditions.