Synthesis, electrochemistry and anticancer activity of novel ferrocenyl phenols prepared via azide-alkyne 1, 3-cycloaddition reaction

D Plażuk, B Rychlik, A Błauż, S Domagała

Index: Plazuk, Damian; Rychlik, Blazej; Blauz, Andrzej; Domagala, Slawomir Journal of Organometallic Chemistry, 2012 , vol. 715, p. 102 - 112

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Citation Number: 13

Abstract

A series of monophenols and diphenols containing the ferrocene-Ctriazolyl and ferrocene- Ntriazolyl bond were prepared in a cycloaddition reaction of ethynylferrocene with aryl and benzyl azides and in a reaction of azidoferrocene with phenylacetylenes, respectively. The anticancer activity of the prepared compounds against hormone-dependent (MCF-7) and hormone-independent (HCC38) breast cancer cell lines was studied. The investigated ...

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