Russian journal of organic chemistry

Reductive acylamination of pyridine N-oxide with aminopyridines and their Np-tolylsulfonyl derivatives

MA Solekhova, YV Kurbatov

Index: Solekhova; Kurbatov Russian Journal of Organic Chemistry, 2005 , vol. 41, # 1 p. 128 - 130

Full Text: HTML

Citation Number: 3

Abstract

Abstract Pyridine N-oxide reacts with 2-and 3-aminopyridines and their Np-tolylsulfonyl derivatives in alkaline medium in the presence of p-toluenesulfonyl chloride to give Np- tolylsulfonyl-2, 2′-and 2, 3′-dipyridylamines, respectively, as a result of reductive acylamination. In the reactions with 4-aminopyridine and 4-p-tolylsulfonyl-aminopyridine, their Np-tolylsulfonyl-and N, N-bis (p-tolylsulfonyl) derivatives are formed, while reductive ...