Abstract: The reaction of a-lithio sulfinamide derivatives with aldehydes and ketones affords P-hydroxy sulfinamides by carbonyl addition. These adducts undergo smooth thermolysis in the range 80-110" to form olefins along with sulfur dioxide and the appropriate amine. These reactions constitute a new synthetic route to olefins. A new and useful one-step synthesis of ketones from esters and a-lithio sulfinamide derivatives is also described. he ...
![Benzhydrol, a-[(butylsulfinyl)methyl]- (8CI) Structure](https://image.chemsrc.com/caspic/061/19977-39-0.png)
