Copper??Catalyzed Synthesis of Nitriles by Aerobic Oxidative Reaction of Alcohols and Ammonium Formate

DKT Yadav, BM Bhanage

Index: Yadav, Dilip Kumar T.; Bhanage, Bhalchandra M. European Journal of Organic Chemistry, 2013 , # 23 p. 5106 - 5110

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Citation Number: 11

Abstract

Abstract An efficient methodology has been developed for the synthesis of nitriles through an aerobic oxidative reaction of alcohols and ammonium formate with copper as a homogeneous catalyst under a normal air atmosphere and solvent-free conditions. This protocol uses the air as a green oxidant and ammonium formate as the nitrogen source. A wide range of substrates were well tolerated in the reaction that gave water as a byproduct.