e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Semisyntheses, X-Ray Crystal Structures and Tubulin-Binding Properties of 7-Oxodeacetamidocolchicine and 7-Oxodeacetamidoisocolchicine
…, RJ Greenwood, MF Mackay, E Hamel, CM Lin
Index: Banwell, Martin G.; Peters, Steven C.; Greenwood, Richard J.; Mackay, Maureen F.; Hamel, Ernest; Lin, Chii M. Australian Journal of Chemistry, 1992 , vol. 45, # 10 p. 1577 - 1588
Abstract Commercially available (–)-colchicine (1) has been converted, via deacetylcolchiceine (4), into a mixture of 7-oxodeacetamidocolchicine (2) and 7- oxodeacetamidoisocolchicine (3). The X-ray structures and tubulin-binding properties of these title ketones are described.
