Tetrahedron: Asymmetry

A practical chemoenzymatic approach to the synthesis of 3-hydroxy metabolites of tibolone

P Ferraboschi, D Colombo, S Reza-Elahi

Index: Ferraboschi, Patrizia; Colombo, Diego; Reza-Elahi, Shahrzad Tetrahedron Asymmetry, 2002 , vol. 13, # 23 p. 2583 - 2586

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Citation Number: 13

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Stereoselective preparation of the 3-hydroxy metabolites of tibolone is easily accomplished by diastereoselective Candida antarctica lipase B-catalyzed transformations of 3α- and 3β-alcohols or acetates mixtures in organic solvents, in suitable amounts for biological studies. ... Tibolone 1 is a synthetic ...