Umpolung of Hemiaminals: Titanocene??Catalyzed Dehydroxylative Radical Coupling Reactions with Activated Alkenes

…, HQ Yuan, CX Ye, J Ma, PQ Huang

Index: Zheng, Xiao; Dai, Xi-Jie; Yuan, Hong-Qiu; Ye, Chen-Xi; Ma, Jie; Huang, Pei-Qiang Angewandte Chemie - International Edition, 2013 , vol. 52, # 12 p. 3494 - 3498 Angew. Chem., 2013 , vol. 125, # 12 p. 3578 - 3582,5

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Citation Number: 18

Abstract

Bis (cyclopentadienyl) titanium (III) chloride(Nugent s reagent)[1] is an efficient single- electron reductant and has been used as a versatile tool in organic synthesis,[2, 3] owing to the ease of handling, its functional-group compatibility, and a broad array of reactions that can be effected under relatively mild conditions. Today,[Cp2TiCl] is used as a catalyst for several types of radical reactions by employing a catalytic amount of [Cp2TiCl2] as a ...