Tetrahedron

Metalation/functionalization sequences applied to 2-bromo-3-fluoroquinolines

L Ondi, JN Volle, M Schlosser

Index: Ondi, Levente; Volle, Jean-Noel; Schlosser, Manfred Tetrahedron, 2005 , vol. 61, # 3 p. 717 - 725

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Citation Number: 17

Abstract

Mono-and disubstituted 2-bromo-3-fluoroquinolines are readily accessible. They can be converted into the 3-fluoroquinoline-2-carboxylic acids by consecutive halogen/metal permutation and into the 2-bromo-3-fluoroquinoline-4-carboxylic acids by consecutive ...

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