Chemistry–A European Journal

Palladium??Catalysed Cyclisation of N??Alkynyl Aminomalonates

W Hess, JW Burton

Index: Hess, Wilfried; Burton, Jonathan W. Chemistry - A European Journal, 2010 , vol. 16, # 41 p. 12303 - 12306

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Abstract

Pyrrolidines and pyrrolidinones are highly important structural motifs in organic chemistry. They are present in many ligands for asymmetric catalysis, as catalysts in the ever-growing field of organocatalysis,[1] and in a vast number of natural products.[2] Moreover, pyrrolidines and nitrogen heterocycles, in general, are exceedingly important motifs in medicinal chemistry. The pursuit of new and efficient methods for the synthesis of ...