Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives

PL Beaulieu, M Bös, Y Bousquet, G Fazal…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 1 p. 119 - 124

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Citation Number: 113

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 4 A significant proportion of the patient population does not respond to therapy and there is an urgent demand for novel strategies addressing this clearly unmet medical need. 5a. ...

New benzimidazoles as thrombopoietin receptor agonists

[Safonov, Igor G.; Heerding, Dirk A.; Keenan, Richard M.; Price, Alan T.; Erickson-Miller, Connie L.; Hopson, Christopher B.; Levin, Jenna L.; Lord, Kenneth A.; Tapley, Peter M. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1212 - 1216]

Synthesis and anticancer evaluation of bis (benzimidazoles),...

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New practical synthesis of the key intermediate of candesart...

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Resistance-modifying agents. 9. 1 synthesis and biological p...

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Catalytic Formation of Ketones from Unactivated Esters throu...

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