Preparation of 10-g quantities of 15-O-acetyl-4-deoxynivalenol

JF Grove, AJ McAlees, A Taylor

Index: Grove, John Frederick; McAlees, Alan J.; Taylor, Alan Journal of Organic Chemistry, 1988 , vol. 53, # 16 p. 3860 - 3862

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Citation Number: 15

Abstract

The most common trichothecenone produced by strains of Fusarium graminearum isolated from Eastern Canadian and United States grain is 15-0-acetyl-4-deoxynivalenol (15-0-acetyl- DON)(1, R= Ac, R'= H1. l Although we have examined 51 isolates of this fungus for their ability to produce this mycotoxin in laboratory culture, the best yield obtained was only 40 mg L-'. The relative inaccessibility of this compound has resulted in the use of ...