The most common trichothecenone produced by strains of Fusarium graminearum isolated from Eastern Canadian and United States grain is 15-0-acetyl-4-deoxynivalenol (15-0-acetyl- DON)(1, R= Ac, R'= H1. l Although we have examined 51 isolates of this fungus for their ability to produce this mycotoxin in laboratory culture, the best yield obtained was only 40 mg L-'. The relative inaccessibility of this compound has resulted in the use of ...