4-Hydroxy-5, 6-dihydropyrones as inhibitors of HIV protease: the effect of heterocyclic substituents at C-6 on antiviral potency and pharmacokinetic parameters

SE Hagen, J Domagala, C Gajda…

Index: Journal of Medicinal Chemistry, , vol. 44, # 14 p. 2319 - 2332

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Citation Number: 53

Abstract

... Journal of Medicinal Chemistry. ... Abstract. Abstract Image. Due largely to the emergence of multi-drug-resistant HIV strains, the development of new HIV protease inhibitors remains a high priority for the pharmaceutical industry. ...

Enantioselective Synthesis of Guaianolides in the Osmitopsin...

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Total synthesis of epothilones B and D: Stannane equivalents...

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Synthèse et réactions S RN 1 en série 5-nitrothiazole

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Über 4??Formyl??thiazole

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