Journal of the American Chemical Society

Hydride vs. electron transfer in the reduction of flavin and flavin radical by 1, 4-dihydropyridines

MF Powell, TC Bruice

Index: Powell, Michael F.; Bruice, Thomas C. Journal of the American Chemical Society, 1983 , vol. 105, # 105 p. 1014 - 1021

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Citation Number: 62

Abstract

Abstract: Literature dealing with the existing controversy concerning the mechanism of hydride equivalent (H-or e-, H', e-) transfer from N-alkyl-l, 4-dihydronicotinamides is presented. Included are references to the dihydronicotinamide reduction of flavins. As a means of assessing the H-and e-, H', e-reduction mechanism of flavins, we have studied the reaction of the N-alky1 [4, 4-1H2]-and-[4, 4-* H2] pyridines 3a-f with the flavin 1 and flavin ...